Comparison of Manual and Automated Methods for Determining Platelet Counts in Dogs with Macrothrombocytopenia
Research output: Contribution to journal › Journal article › Research › peer-review
Platelet counts were performed in 43 Cavalier King Charles Spaniels (CKCS, a breed predisposed to macrothrombocytopenia) and in 10 control dogs using 3 automated systems and 3 manual methods (erythrocytelysing agents + counting chamber or evaluation of blood smear). Good correlations were found between platelet counts using all methods (all P < 0.0001; R2 = 0.71-0.85). Best correlations were found between the manual methods. Significantly larger platelets were found in CKCS with platelet count <100,000/μl when compared with control dogs and CKCS with platelet count >100,000/μl (both P < 0.0001). All platelet counts - except when made with the 2 counting chamber methods - were underestimated at platelet counts ≤100,000/μl.
Original language | English |
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Journal | Journal of Veterinary Diagnostic Investigation |
Volume | 16 |
Issue number | 2 |
Pages (from-to) | 167-170 |
Number of pages | 4 |
ISSN | 1040-6387 |
DOIs | |
Publication status | Published - 2004 |
ID: 226213698