Comparison of Manual and Automated Methods for Determining Platelet Counts in Dogs with Macrothrombocytopenia
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Comparison of Manual and Automated Methods for Determining Platelet Counts in Dogs with Macrothrombocytopenia. / Olsen, Lisbeth H.; Kristensen, Annemarie T.; Qvortrup, Karen; Pedersen, Henrik D.
In: Journal of Veterinary Diagnostic Investigation, Vol. 16, No. 2, 2004, p. 167-170.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Comparison of Manual and Automated Methods for Determining Platelet Counts in Dogs with Macrothrombocytopenia
AU - Olsen, Lisbeth H.
AU - Kristensen, Annemarie T.
AU - Qvortrup, Karen
AU - Pedersen, Henrik D.
PY - 2004
Y1 - 2004
N2 - Platelet counts were performed in 43 Cavalier King Charles Spaniels (CKCS, a breed predisposed to macrothrombocytopenia) and in 10 control dogs using 3 automated systems and 3 manual methods (erythrocytelysing agents + counting chamber or evaluation of blood smear). Good correlations were found between platelet counts using all methods (all P < 0.0001; R2 = 0.71-0.85). Best correlations were found between the manual methods. Significantly larger platelets were found in CKCS with platelet count <100,000/μl when compared with control dogs and CKCS with platelet count >100,000/μl (both P < 0.0001). All platelet counts - except when made with the 2 counting chamber methods - were underestimated at platelet counts ≤100,000/μl.
AB - Platelet counts were performed in 43 Cavalier King Charles Spaniels (CKCS, a breed predisposed to macrothrombocytopenia) and in 10 control dogs using 3 automated systems and 3 manual methods (erythrocytelysing agents + counting chamber or evaluation of blood smear). Good correlations were found between platelet counts using all methods (all P < 0.0001; R2 = 0.71-0.85). Best correlations were found between the manual methods. Significantly larger platelets were found in CKCS with platelet count <100,000/μl when compared with control dogs and CKCS with platelet count >100,000/μl (both P < 0.0001). All platelet counts - except when made with the 2 counting chamber methods - were underestimated at platelet counts ≤100,000/μl.
U2 - 10.1177/104063870401600215
DO - 10.1177/104063870401600215
M3 - Journal article
C2 - 15053372
AN - SCOPUS:1642359327
VL - 16
SP - 167
EP - 170
JO - Journal of Veterinary Diagnostic Investigation
JF - Journal of Veterinary Diagnostic Investigation
SN - 1040-6387
IS - 2
ER -
ID: 226213698