Tissue factor activated thromboelastography correlates to clinical signs of bleeding in dogs
Research output: Contribution to journal › Journal article › Research › peer-review
There were statistically significant differences between all TEG values of hypo- and normo- and hyper-coagulable dogs. Thromboelastography correctly identified dogs with clinical signs of bleeding with a positive predictive value (PPV) of 89% and a negative predictive value (NPV) of 98% based on G alone. In comparison, the coagulation profile had a PPV between 50-81% and a NPV between 92-93% for detection of bleeding, depending on the observer. In conclusion, a TF-activated TEG G value < 3.2K dyn/cm2 correctly identified dogs with clinical signs of bleeding with very high PPV and NPV, irrespective of observer. The findings strongly suggest that TF- activated TEG may be of value in the workup of dogs suspected of having a haemostatic disorder.
Original language | English |
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Journal | Veterinary Journal |
Volume | 179 |
Issue number | 1 |
Pages (from-to) | 121-129 |
Number of pages | 9 |
ISSN | 1090-0233 |
DOIs | |
Publication status | Published - 2009 |
ID: 15400593